ZFP36 and juvenile idiopathic arthritis: Genome-wide association studies (GWAS) have highlighted the association of ZFP36 family members with pathogenic mechanisms in various autoimmune diseases. Twenty-eight single-nucleotide polymorphisms (SNPs) in the ZFP36 gene were found in patients with autoimmune disorders such as rheumatoid arthritis (RA), psoriasis, multiple sclerosis (MS), and juvenile idiopathic arthritis (JIA) (42).