Genome-wide association studies (GWAS) have highlighted the association of ZFP36 family members with pathogenic mechanisms in various autoimmune diseases. Twenty-eight single-nucleotide polymorphisms (SNPs) in the ZFP36 gene were found in patients with autoimmune disorders such as rheumatoid arthritis (RA), psoriasis, multiple sclerosis (MS), and juvenile idiopathic arthritis (JIA) (42). This evidence concerns the gene ZFP36 and multiple sclerosis.