The percentages of both CD86+ and CD274+ pDCs were significantly higher in scrub typhus patients compared to the HCs (for CD86+ pDCs, median 39.9% versus 11.3%, P = 0.031; and for CD274+ pDCs, 13.6% versus 0.2%, P = 0.001; Figures 2A, B). Here, CD86 is linked to scrub typhus.