Some DEGs including SERPINA3, SLPI, CBF, FTCD, TASPN7, VCAN, TIMP1 and FOS might be novel biomarkers to facilitate timely diagnosis and early therapeutic intervention in donor kidney preservation, implantation or post-transplantation, in particular, effectively improve the donor quality and allograft survival of DD. Here, SERPINA3 is linked to dentin dysplasia.