Patients in group I had higher prevalence of hypocortisolism (38.5 vs 6.8%, p=0.012), lower ACTH (16.3 vs 32.1pg/ml, p=0.234) and DHEAS (86.29 vs 117.8μg/dl, p= 0.086) as compared to group II. This evidence concerns the gene SULT2A1 and adrenocortical insufficiency.