IFNB1 and abortion: Effects on spontaneous abortion were also confirmed in an Italian population of 92 pregnancies exposed to the drug, demonstrating that NTZ exposure to up to 12 weeks of gestation was associated with spontaneous abortion (odds ratio [OR] 3.9, 95% confidence interval [CI] 1.9–8.5, p <0.001) if compared to IFNβ exposure or no exposure.