TNF and hydrops fetalis: But a recent research indicated that in non-reperfused MI-induced HF mice, myocardial infiltrating CD4+Foxp3+ Treg cells exhibited proinflammatory TH1-type features with the expression of IFN-γ, TNF-α, and TNFR1 and had decreased immunomodulatory capacity with potentiated antiangiogenic and profibrotic properties.