NOS2 and pulmonary emphysema: In a mouse model with emphysema, after the inhibition of iNOS was observed a significant regeneration of the lung (Fysikopoulos et al., 2020), but these results contrast with those obtained by the group of Boyer et al. (2011) in which inhibition of iNOS activity reduced protein nitration and protein oxidation without effect on inflammation, proliferation, and development of emphysema.