In addition to diabetes and atherosclerosis, PKC regulates several cellular functions, including cell death and proliferation, gene transcription and translation, alteration of cell shape and migration, regulation of cell-cell contact and secretion, and regulation of ion channels and receptors, which is involved in several diseases, such as cancer, heart failure, stroke, neurodegenerative diseases, autoimmune diseases, and psychiatric disorders (Mochly-Rosen et al., 2012). The gene discussed is PRRT2; the disease is diabetes mellitus.