SENP1 expression was demonstrated significant positive correlations with B cells in 31 cancers, CD4+ T cells in 31 cancers, neutrophils in 31 cancers, macrophage cells in 30 cancers, DC in 29 cancers, CD8+ T cells in 29 cancers, Tregs in 27 cancers, NK cells in 26 cancers, mast cells in 24 cancers, and monocytes in 23 cancers. The gene discussed is CD4; the disease is cancer.