BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Three of the five breakpoints were previously identified in CML patients (BCR-ABL1INS/Del, BCR-ABL1e13a3 and BCR-ABL1e14a3) while two were purposefully engineered in our laboratory (BCR-ABL1∆DC2 and BCR-ABL1∆SH3).