Hb response data were extractable from thirteen trials Besarab et al. (2015), Chen et al. (2017), NCT01888445 (2018), Akizawa et al. (2019a), Chen et al. (2019a), Chen et al. (2019b), NCT02278341 (2019), Coyne et al. (2021), Fishbane et al. (2021), NCT02021318 (2021), Provenzano et al. (2021), Shutov et al., (2021) (five trials for DD-CKD patients, eight trials for NDD-CKD patients) with 7,488 participants enrolled. The gene discussed is GSTM1; the disease is dentin dysplasia.