This is in consonance with other studies (Alattar et al., 2020; Antwi-Amoabeng et al., 2020; Conrozier et al., 2020; Knorr et al., 2020; Morrison et al., 2020; Pérez-Sáez et al., 2020) and suggests that CRP may be used as a prognostic biomarker after TCZ administration in COVID-19 severe patients. This evidence concerns the gene CRP and COVID-19.