Beyond the recognized AD genes identified in the gene lists garnered from the GWAS and single-cell RNA-seq studies, several other genes (TREM2, CD33, CHRNA2, PRSS8, ACE, TKT, APP, and GABRA1) were found to be the targets of clinical AD drugs reported by Cummings et al. (2019). This evidence concerns the gene TKT and Alzheimer disease.