Key results of the general linear model with CSF Aβ42, t-tau, and p-tau as the dependent variables and covariates: age, sex, education, APOEε4 status, among participants from the Alzheimer's Disease Neuroimaging Initiative cohort with Alzheimer's disease dementia (participants meeting A+ T+ criteria). The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.