Different genes have been associated to ALS pathology including those encoding for Cu-Zn superoxide dismutase 1 (SOD1), Tar DNA binding-protein 43 (TDP-43), fused in sarcoma/translocated in liposarcoma (FUS), or chromosome 9 open reading frame 72 (C9orf72). Here, C9orf72 is linked to amyotrophic lateral sclerosis.