KCNMA1 and Stroke: Figure 5A shows the timeline of animal experiments. First, we recorded weight changes of three groups. As shown in Figure 5B, mice lost the most weight at 3 days and there was no significant difference among groups during 14 days after tMCAO. Then, we investigated the number of surviving mice and found that about more than 80% of mice of the Paxilline group failed to live at 14 dpi (Figure 5E), which suggests that inhibition of BK channels at the acute phase affected the survival rate after stroke.