Acromegaly is most commonly caused by a growth hormone (GH)-secreting pituitary adenoma, whereas Cushing’s disease results from an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma, with consequent overproduction of insulin-like growth factor 1 (IGF-1) and cortisol, respectively [1]. The gene discussed is GH1; the disease is acromegaly.