SYP expression was more prevalent in the samples, and was shown to be associated with WNT2 expression, especially in the adenoma cells (normal sample P-value: 0.0025, 95% CI 0.0014–0.0048; adenoma sample P-value: 8.864E-07, 95% CI 0.017–0.025, two-sided exact binomial test, Fig. 4). This evidence concerns the gene SYP and adenoma.