FASLG and neoplasm: FHVH1 CAR-T cells stimulated by CD5+ target cells CCRF-CEM showed a slightly higher median fluorescence intensity of Fas ligand (FasL) than either FHVH3/VH1, FHVH3, or H65 (p < 0.05; Figure 4D), although T cells showed both enhanced killing activity against tumor cells and an increased risk of activation-induced cell death (AICD) as a result of augmented FasL expression.29