Furthermore, like LCAT3 knockdown, FUBP1 knockdown also suppressed the migration of A549 and Calu1 lung cancer cells (Fig. 6E, F), and triggered G1 arrest (Fig. 6H, I) by significantly reducing the levels of cyclin A2 and cyclin D1 (Fig. 6G). The gene discussed is CCND1; the disease is lung cancer.