In addition, Qi et al. find that the expression of LINC01278 in osteosarcoma tissues is enhanced, is the increased linc01278 expression is related to clinical staging, distant metastasis and poor prognosis of patients, and LINC01278 promotes the proliferation of osteosarcoma cells through miR-133a-3p/PTHR1 signal [18]. This evidence concerns the gene PTH1R and osteosarcoma.