Such a 450-gene panel for intellectual deficiency showed a heterozygous duplication of a single nucleotide, Chr7(GRCh37): g.70236569dup, ENST00000342771.4: c.1769dup in exon 11 of AUTS2, leading to a frame shift expected to produce a premature stop codon, p.(Met593Tyrfs*85). This evidence concerns the gene AUTS2 and Intellectual disability.