mRBP-coding genes with broader tissue expression and dysregulation in DCM included the mRNA splicing factor gene SLM2 (KHDRBS3 or T-STAR) (1.88-fold change, P = 0.0015) and RNA binding protein, mRNA processing factor 2 (RBPMS2) (1.49-fold change, P = 0.010), indicating their potential role in DCM pathogenesis (Figure 1A). The gene discussed is KHDRBS3; the disease is familial dilated cardiomyopathy.