Because MALT1 may enhance inflammatory cytokine production in endothelial cells and induce endothelial dysfunction, and these physiological changes indicate further atherosclerosis, thrombosis formation, and AIS occurrence and also MALT1 regulates Th cell differentiation and their related inflammatory cytokine excretion; therefore, we hypothesized that MALT1 measurement might play a pivotal role for AIS management.10, 11, 12, 18, 19, 20. The gene discussed is MALT1; the disease is endothelial dysfunction.