ALKBH3 and Familial prostate cancer: Compared with normal tissues, ALKBH3 is highly expressed in pancreatic (Konishi et al. 2005), lung (Tasaki et al. 2011), and urothelial cancers (Shimada et al. 2012), and is evenly identified as the high-grade prostate cancer marker, implying that ALKBH3 may function in the tumorigenesis process and would be helpful for the early diagnosis.