METTL3 and acute myeloid leukemia: The expression levels of METTL3 and METTL14 are more abundant in AML (Vu et al. 2017; Weng et al. 2018), and METTL3 is captured by a genome-wide CRISPR dropout screening, and identified as a necessary gene for AML cell growth (Barbieri et al. 2017).