The results showed that, although GSK650394 could inhibit SGK1 expression in vivo (Supplementary Fig. S7C, D), it did not affect tumor growth (Fig. 4F) or weight (Supplementary Fig. S10A), whereas the number of metastases on the lung surface in the Dex+GSK group was significantly decreased compared with that in the Dex-only group (Fig. 4G and Supplementary Fig. S10B, C). The gene discussed is SGK1; the disease is neoplasm.