Moreover, FAT1, ARID2, CASP8, CREBBP, AJUBA, PTEN, PIK3CA, EZH2, KRAS, CCND1, and MTOR were nominated in 1–3 studies each as well as by us, lending credibility to their pathogenic roles in cutaneous squamous cell carcinoma. This evidence concerns the gene CREBBP and cutaneous squamous cell carcinoma.