Instead, the majority of these 13 pathways were notably cancer-related, including ErbB signaling pathway, mTOR signaling pathway, glioma, HIF-1 signaling pathway, non-small cell lung cancer, breast cancer, choline metabolism in cancer as well as EGFR tyrosine kinase inhibitor resistance (Fig. 7b). The gene discussed is EGFR; the disease is central nervous system cancer.