For example, the lncRNA LNCAROD acts as a scaffold for the interaction between YB-1 and HSPA1A, prevents YB-1 proteasome degradation in head and neck squamous cell carcinoma (HNSCC) cells, and promotes the malignant behavior of HNSCC cells21. The gene discussed is HSPA1A; the disease is head and neck squamous cell carcinoma.