The availability of TCRs directed against 7-16V/HLA-A*03:01 (TCRA3V), 7-16V/HLA-A*11:01 (TCRA11V), and 10-19R/HLA-B*07:02 (TCRB7R) permitted their use as sensitive probes demonstrating the presence of these p-HLA complexes on the cell surface of various cancer cell lines from multiple histologies. The gene discussed is HLA-A; the disease is cancer.