Indeed, it is remarkable that a single addition of a low Blina dose at the beginning of the expansion led to the successful removal of tumor cells in just 2 weeks, whereas others reported that the BsAb had to be added every 2–4 days for about 3 weeks, to achieve the elimination of CD19+ CLL cells in T cell expansion culture.46 The complete elimination of the neoplastic component provides a double advantage. The gene discussed is CD19; the disease is neoplasm.