In particular, mice receiving CIK +OBI showed a significantly higher density of both CD3+ cells (31.91±48.87 cell counts/mm2 in CIK +Iso vs 503±943.7 cell counts/mm2 in CIK +OBI; figure 5B) and CD3+CD56+ CIK cells (0.13±0.6 cell counts/mm2 in CIK +Iso vs 28.51±52.85 cell counts/mm2 in CIK +OBI; figure 5C) within the tumor mass. The gene discussed is NCAM1; the disease is neoplasm.