KRAS and neoplasm: First, there was a striking stability of the mutated KRAS AF of around 33% between the initially developed SR tumor C3 and all subsequent tumors generated via re-implantation (note that the AF of around 33% in the ddPCR analysis is somewhat higher than in BEAMing and WES, suggesting an overestimation of the AF in the ddPCR for technical reasons).