In addition, drug treatment exhibited a strong effect on signaling, which seemed to be homogenized within each group with dissimilarities lower than that of healthy and untreated donors (median Jaccard distance to each group’s mean network: EGCG = 0.512, untreated MS = 0.641; FTY = 0.595, untreated MS = 0.646; GA = 0.632, untreated MS = 0.665; NTZ = 0.615, untreated MS = 0.641; IFN = 0.599, untreated MS = 0.615). Here, IFNA1 is linked to myeloid sarcoma.