IL4 and asthma: Among others an increase in interferon gamma and a decrease in interleukin 4 (IL4) levels in asthmatic children [17] has been observed, as well as a decrease in Th2 response cytokines in mice with artificially induced asthma model [20], or, based on the increase in interleukin 2 (IL2) and decrease in IL4, in rats subjected to forced swimming and food restriction [21].