In CF mice with PA lung infection, the administration of 8.3 mg/kg i.p. of ODSH did not significantly decrease airway HMGB1 levels (1.22 ± 0.31 AU), compared to CF mice treated with vehicle (1.13 ± 0.19 AU) (Fig. 5B). Here, HMGB1 is linked to cystic fibrosis.