Chemotherapy can cause thyroid dysfunction and response to treatment may be affected by pre-existing thyroid conditions.33–35SLC26A7 is also expressed in parietal cells and genetic deletion results in decreased gastric acid secretion.36,37 Both thyroid and gastric dysfunction can cause vomiting.38,39 Therefore, SLC26A7 represents a strong biological candidate for vomiting, but lacks genetic validation. The gene discussed is SLC26A7; the disease is thyroid gland disorder.