BCL6 and COVID-19: In deceased donors with COVID-19, Kaneko et al. found that BCL6-expression in germinal center Tfh was lost within thoracic lymph nodes, suggesting that Tfh response formation may be impaired in severe SARS-CoV-2 infection [39], but the formation of antigen-specific Tfh responses, particularly in milder cases of COVID-19, remains unclear.