TIMP1 and retinitis pigmentosa 1: Using either a recombinant TIMP-1, a synthetic chemical compound SB-3CT, or clusterin [14, 15, 17], our observations documented that these compounds inhibit the cone mosaic rearrangements, an event observed prior to cone cell death in RP retina, by affecting the reactive gliosis of the MGCs in the retina [18, 19].