Suppression of P-GP by miR-3682-3p mimics or XR-9576 could significantly reverse BMI1-mediated chemoresistance of bladder cancer cells, presenting miR-3682-3p or XR-9576 as a potential adjuvant agent in GC-chemoresistant bladder cancer with ectopic BMI1 expression. This evidence concerns the gene PGP and urinary bladder carcinoma.