PCSK9 and heart disorder: Hydrolysis of lipoprotein lipase is the basis for the increase in plasma triglycerides.19 Indeed, in patients without cardiac disease, it has been noted that any increase in the level of PCSK9 implies an increase in the cardiovascular risk.26 In our study (Table 4), the probability of having a cardiovascular event in this population is associated with the PCSK9 level.