PPARGC1A and Cachexia: The suppression of AMPK phosphorylation did not coincide with the lack of changes to PGC‐1α expression, and differential effects of cachexia on AMPK signaling and PGC‐1α expression have been previously reported (Puppa et al., 2012, 2014; White, Puppa, Gao, et al., 2013).