In addition, for infertile patients, sperm acrosome enzyme is a crucial basis and identification method for judging sperm quality, combined with the conventional parameters of semen, the sperm acrosin activity can be better evaluated sperm function and provide a basis for diagnosis and treat of the disease (Cui et al., 2000; Langlois et al., 2005). The gene discussed is ACR; the disease is Infertility.