For example, A20 is commonly inactivated by biallelic somatic loss of function mutations or genomic deletions in various B cell lymphomas, including marginal zone lymphomas, diffuse large B-cell lymphoma (DLBCL), MALT lymphoma, primary mediastinal B cell lymphomas and Hodgkin's lymphoma [331–334]. Here, TNFAIP3 is linked to diffuse large B-cell lymphoma.