Germline SNPs in TNFAIP3 (encoding A20) are associated with Crohn's disease [310], coeliac disease [311], type 1 diabetes [312], RA [313,314], coronary artery disease in type 2 diabetes [315], systemic sclerosis [316], psoriasis [317] and systemic lupus erythematosus (SLE) [318,319]. The gene discussed is TNFAIP3; the disease is systemic sclerosis.