ACE2 and obesity due to melanocortin 4 receptor deficiency: It is possible that due to elevated glucose levels, as frequently observed in obesity and MetS, the glycolysis‐mediated ACE2 upregulation in the lung macrophages of these patients subsequently increases SARS‐CoV‐2 cell invasion, contributing to an increased risk to get infected with SARS‐CoV‐2 (Figure 1).