AKT1 and neoplasm: Phosphatase and tensin homolog (PTEN) (OMIM 601728) is a tumor suppressor negatively regulates Phosphoinositide 3‐kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway that plays an important role in cell growth, survival, and proliferation (Lv et al., 2013).