What an interesting thing is that study had showed that paxillin, which served as a crucial scaffolding and signal integrator, bound directly to microtubule‐associated protein 1 light chain 3 (LC3) through a conserved LC3‐interacting region (LIR) motif to stimulate FA disassembly and promote tumor cell metastasis.36 This evidence concerns the gene MAP1LC3A and neoplasm.