Based on the Kaplan-Meier survival plotter database, in BC, a high level of STARD3 mRNA was significantly associated with worse OS (P = 9.7E-6\ HR = 1.67), RFS (P = 0.00029\ HR = 1.25) and DMFS (P = 6.6E-5 \HR=1.52) compared with a low level of STARD3. In addition, in BC, a high level of STARD3 mRNA was significantly associated with poor OS in HER+ patients compared with a low level of STARD3 mRNA (P = 0.019\HR = 3.95) (Figure 4, A and B). This evidence concerns the gene STARD3 and breast cancer.