AQP3 and hepatocellular carcinoma: Interestingly, another aquaglyceroporin, AQP3, which was reported to be involved in P. berghei development within human hepatoma cells and in P. vivax development within human primary hepatocytes but is not essential for sporozoite invasion (Posfai et al., 2018; Posfai et al., 2020), was not found to be significantly differentially expressed between the two cell types (HH/HC ratio of 2.3) (Figure 1A).