HDAC1 and malaria: These compounds are both hydroxymate-based inhibitors that target affect multiple stages of malaria parasites (Andrews et al., 2012; Coetzee et al., 2020) by inhibiting multiple HDACs, particularly HDAC1 (PF3D7_0925700) and HDA1 (PF3D7_147220) (Coetzee et al., 2020).