POLR2F and Miyoshi myopathy: The violin plots showed significantly higher expression of MIF and two other co-expressed genes D-Dopachrome Tautomerase (DDT) and RNA Polymerase II Subunit F (POLR2F) in cluster #5, the co-expressions were validated in BM MM cells from multiple patient datasets (GSE26760, GSE19784, GSE9782) (26–28), which suggested cluster #5 was likely the initial state of these plasma cells (Figure 5C and Supplementary Figure 5B).